From a
public health standpoint, it would be better to vaccinate many people with
lower doses than fewer people with full doses when vaccine supplies are scarce,
said Padma Shri Awardee Dr A M Pillai National President and Padma Shri Awardee
Dr K K Aggarwal Honorary Secretary General IMA.
A study published in 2009 in Archives of Internal Medicine has shown that half dose flu shots are effective in adults, especially in women
and those younger than 50, and offer a viable way to stretch supplies during
vaccine shortages.
Earlier in June 2000, a NIAID conducted trial, published in journal
Vaccine concluded that the immune responses to the full dose were higher, on
average, than immune responses to the half dose vaccine but should a public
health emergency arise, half-dose influenza vaccines for healthy adults might
be an acceptable strategy if the vaccine supply is substantially limited.
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