Friday, 14 October 2016

New updated RBC transfusion guidelines

New updated RBC transfusion guidelines AABB, earlier known as the American Association of Blood Banks, has published new guidelines to help clinicians in decision making about red blood cell (RBC) transfusion “Clinical Practice Guidelines from the AABB: Red Blood Cell Transfusion Thresholds and Storage” were published online October 12, 2016 in JAMA. These guidelines are an update of the RBC transfusion guidelines that were released in 2012. The Expert Panel recommends: • A restrictive RBC transfusion threshold of 7 g/dL in hospitalized hemodynamically stable adult patients, including critical care patients instead of the currently recommended 10 g/dL. • An RBC transfusion hemoglobin threshold of 8 g/dL and a target of 8 to 10 g/dL for patients with acute coronary syndrome. • A restrictive RBC transfusion threshold of 8 g/dL for patients undergoing orthopedic surgery, cardiac surgery and those with pre-existing cardiovascular disease. • Patients, including neonates requiring transfusions, should receive standard issue (RBC units selected at any point within their licensed dating period) rather than only fresh RBC units that have been stored for less than 10 days. • Single-unit transfusions should be considered for patients without active bleeding. These recommendations are not applicable to patients with severe thrombocytopenia (patients treated for hematological or oncological reasons who are at risk of bleeding) and chronic transfusion–dependent anemia (not recommended due to insufficient evidence). Individual thresholds and hemoglobin concentration targets should be considered for patients who need regular blood transfusions for chronic anemia. (Source: AABB)

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